Cytokines as inflammatory mediators.

The role of cytokines as inflammatory mediators in preeclampsia

INTRODUCTION This study is to determine the concentrations of IL-6, TNF α, and C reactive protein (CRP) in women with severe preeclampsia, and compare with those of gestational age- matched normotensive pregnant women and to correlate CRP levels with markers of organ damage in women with preeclampsia. METHODS This was a case control study of fifty women with severe preeclampsia and fifty gest...

Circulating cytokines as mediators of fever.

The febrile response is thought to be mediated by endogenous mediators, generically called "endogenous pyrogens." In the classical model of pathogenesis, induction of fever is mediated by the release of pyrogenic cytokines such as tumor necrosis factor (TNF), interleukin (IL)-1, IL-6, and interferons into the bloodstream in response to exogenous pyrogens. These mediators act at the level of the...

Inflammatory cytokines in heart failure: mediators and markers.

Evidence from both experimental and clinical trials indicates that inflammatory mediators are of importance in the pathogenesis of chronic heart failure (HF) contributing to cardiac remodeling and peripheral vascular disturbances. Several studies have shown raised levels of inflammatory cytokines such as tumor necrosis factor (TNF)α, interleukin (IL)-1β and IL-6 in HF patients in plasma and cir...

Inflammatory Mediators and Cytokines by Inflammatory Cells and Induced by Preprosomatostatin Messenger RNA Is Expressed

Cytokines as mediators in the pathogenesis of septic shock.